ZO Skin Health Renewal Crème

Size: 50 mL / 1.7 Fl. Oz.

This product contains retinol.

Suitable for dry, sensitized, oily, or acne-prone skin

ZO® Renewal Crème is a lightweight, retinol-infused moisturizer that delivers powerful hydration while calming irritation and restoring skin health. Designed to improve skin texture and resilience, this multi-action formula visibly reduces the appearance of fine lines and wrinkles, evens skin tone, and minimizes redness.

With a fast-absorbing, weightless texture, this crème deeply hydrates without clogging pores—making it especially suitable for oily, acne-prone, or post-procedure skin. A blend of emollients, probiotics, peptides, and antioxidants supports the skin’s natural barrier and promotes a smoother, more radiant complexion.

Fragrance-free and suitable for daily use.

Benefits

• Promotes rapid, long-lasting hydration with a non-greasy feel
• Strengthens the skin’s protective barrier for a healthier, more even appearance
• Softens the look of fine, dynamic lines
• Calms visible redness and soothes sensitized skin
• Free of added fragrance for gentle use on sensitive skin

Before and After

Protocol: a 12-week third-party clinical study of 42 subjects to assess the efficacy potential of Renewal Crème. Subjects represent females, ages 42-65, with Fitzpatrick skin types I-IV. Supported with use of Gentle Cleanser and Sunscreen + Primer SPF 30 during the study.

How to Use

Apply to clean, dry skin once or twice daily, as needed.

Use in the morning, evening, or both.

Key Ingredients

• Acetyl Hexapeptide-8 – A peptide that helps reduce visible signs of aging by softening expression lines
• Lactococcus Ferment Lysate – Probiotic-derived to support skin’s barrier and promote a healthier appearance
• Polyglutamic Acid – A naturally derived humectant that delivers intense hydration and plumps the skin
• Light Emollient Blend (Jojoba Esters, Sodium Hyaluronate) – Replenishes lipids and restores the skin barrier without heaviness

Full Ingredient List

Aqua/Water/Eau, Isocetyl Stearate, Isopropyl Palmitate, Cetearyl Alcohol, Glycerin, Lactococcus Ferment Lysate, Jojoba Esters, Silica, Steareth-21, Steareth-2, Polysorbate 60, Polysorbate 20, Cocos Nucifera (Coconut) Oil, Glycine Soja (Soybean) Oil, Avena Sativa (Oat) Kernel Extract, Epilobium Angustifolium Flower/Leaf/Stem Extract, Gardenia Taitensis Flower Extract, Plankton Extract, Glycine Soja (Soybean) Sterols, Tocopherol, Retinol, Magnesium Ascorbyl Phosphate, Ectoin, Caprylyl Glycol, Polyglutamic Acid, Hexylene Glycol, Hydrogenated Lecithin, Lecithin, Ubiquinone, Acetyl Hexapeptide-8, Tetrasodium EDTA, Sodium Hyaluronate, Carbomer, Sodium Hydroxide, Citric Acid, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Sorbic Acid, Potassium Sorbate.

Note: ZO Skin Health continually updates formulas to align with global ingredient standards. For the most accurate ingredient list, refer to the product packaging.