ZO Skin Health Clear Renewal

Size: 50 mL / 1.7 fl. oz.

Skin Concerns: Acne-prone skin, blemishes, clogged pores, post-acne marks, post-inflammatory discoloration, excess oil, congestion, uneven skin texture, visible redness, early signs of aging

Skin Types: Oily, combination, and blemish-prone skin

Texture: Lightweight corrective retinol treatment with advanced encapsulated delivery technology

Recommended Use: Blemish correction, oil control, post-acne mark reduction, and skin renewal. Morning or evening as tolerated.

ZO Skin Health Clear Renewal is a next-generation retinol treatment developed specifically for oily, congested, and blemish-prone skin experiencing persistent breakouts, excess surface oil, uneven texture, and lingering post-acne marks. Combining 0.3% encapsulated retinol with 1% salicylic acid and advanced skin-balancing technologies, this targeted corrective formula helps visibly refine pores, smooth rough texture, and reduce the appearance of post-blemish discolouration while supporting a clearer, healthier-looking complexion.

Blemish-prone skin often experiences more than active breakouts. Even after blemishes subside, residual discoloration, uneven texture, enlarged-looking pores, and excess oil can remain, making the complexion appear congested and irregular. Traditional acne treatments may address surface oil or individual breakouts without supporting the skin renewal processes needed to improve these lingering concerns. Clear Renewal takes a more comprehensive approach by targeting visible blemishes, post-acne marks, congestion, and premature signs of aging within one advanced treatment.

At the heart of the formula is ZO-RDS™ Retinol Delivery System, ZO Skin Health’s exclusive biomimetic liposomal technology designed to deliver retinol through a controlled-release mechanism. This innovative encapsulation helps protect retinol against oxidation and degradation while supporting targeted delivery and improved skin tolerability. By promoting natural cellular turnover, the 0.3% retinol helps refine the appearance of uneven texture, reduce visible post-blemish marks, and support smoother-looking skin.

The formula is further enhanced with 1% Salicylic Acid, a beta hydroxy acid recognized for its ability to exfoliate within pores and help remove accumulated oil and dead surface cells. This pore-focused action complements retinol’s renewing benefits by addressing congestion and excess sebum, two common contributors to blemish-prone skin.

Additional targeted ingredients, including Potassium Azeloyl Diglycinate, Rose Canina Fruit Extract, Cetyl Tranexamate Mesylate, and ZO-RRS2 technology, complement the formula’s focus on visible redness, uneven tone, and skin resilience. Together, these ingredients help promote a more balanced complexion while supporting skin comfort throughout the corrective process.

Unlike conventional retinol treatments focused primarily on wrinkles or pigmentation, ZO Clear Renewal is specifically formulated to address the intersection of blemishes, post-acne discoloration, excess oil, and visible aging. Its targeted approach makes it particularly relevant for adults experiencing persistent breakouts alongside uneven texture, residual marks, and early signs of aging.

With consistent use, skin appears clearer, smoother, and more refined, with reduced visible congestion, improved tone uniformity, and a healthier-looking balance.

How to use

• When to Apply: Apply AM or PM
• How to Apply: Apply one pump to clean, dry skin once per day for the first week and twice per day thereafter.
• Fitting into Your Routine: After completing the Getting Skin Ready regimen to cleanse, exfoliate, and tone the skin, apply Clear Renewal as Step 2 of your ZO regimen, followed with a broad-spectrum sunscreen with SPF 30 or higher as the final step in the morning.
• What to Expect: Visible reduction in the appearance of post-blemish marks and excess surface oil, refined look of skin texture for a smoother complexion.
• What to Avoid: Avoid excessive sun exposure. Avoid using on irritated or compromised skin and applying immediately after aggressive procedures (chemical peels, laser treatment, etc.). Consult a physician prior if using products with benzoyl peroxide or salicylic acid, topical antibiotics or oral isotretinoin.

What Makes This Unique

ZO-RDS™ Retinol Delivery System

ZO-RDS™ is ZO Skin Health’s exclusive retinol encapsulation technology, utilizing a biomimetic liposomal system engineered for controlled release and targeted delivery.

Traditional retinol formulas can be associated with dryness, redness, and irritation, particularly when introduced into an active skincare routine. ZO-RDS™ helps address these challenges by protecting retinol against oxidation and degradation while optimizing its delivery.

Within Clear Renewal, this technology supports cellular turnover, visible texture refinement, and improvement in post-blemish marks while helping minimize irritation.

0.3% Encapsulated Retinol

Retinol supports natural cellular turnover to help improve uneven texture, visible congestion, and discoloration associated with previous blemishes.

Its renewing action also helps address early signs of aging, making Clear Renewal suitable for adults experiencing both breakouts and age-related texture changes.

1% Salicylic Acid

Salicylic Acid is an oil-soluble beta hydroxy acid that exfoliates within pores to help remove excess sebum and accumulated surface cells.

Its pore-focused action helps improve the appearance of congestion, refine skin texture, and support a clearer-looking complexion.

ZO-RRS2 Technology

A featured proprietary ZO Skin Health technology included within Clear Renewal’s multi-action corrective formula.

It complements the treatment’s focus on visible redness and skin comfort.

Potassium Azeloyl Diglycinate

A multifunctional ingredient that helps support a more balanced-looking complexion by addressing visible oiliness and uneven skin tone.

It complements the formula’s focus on blemish-prone skin and post-inflammatory discoloration.

Rose Canina Fruit Extract

A botanical ingredient that provides antioxidant and skin-conditioning support.

It helps complement the formula’s corrective approach while supporting overall skin quality.

Cetyl Tranexamate Mesylate

A targeted ingredient selected to support the appearance of more even skin tone and improve visible discoloration associated with post-blemish marks.

Together, these technologies provide a comprehensive approach to blemish-prone skin by combining cellular renewal, pore exfoliation, oil balance, and visible tone correction.

Ingredients

Aqua/Water/Eau, Glycerin, Cetearyl Alcohol, Dimethicone, Propanediol, Arachidyl Alcohol, Pentylene Glycol, Cetyl Tranexamate Mesylate, Potassium Azeloyl Diglycinate, Salicylic Acid, Sclerotium Gum, Phosphatidylcholine, Butylene Glycol, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Polyglyceryl-10 Laurate, Sodium Polyacrylate, Behenyl Alcohol, Bakuchiol, Cetyl Glyceryl Ether, Isohexadecane, Cetearyl Glucoside, Arachidyl Glucoside, Retinol, Sodium Ascorbyl Phosphate, Sodium Gluconate, Niacinamide, Caprylhydroxamic Acid, Polydextrose, Polysorbate 80, Citric Acid, Caffeine, Cetyl Alcohol, Ascorbyl Palmitate, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Sodium Bisulfite, Sodium Metabisulfite, Tocopheryl Acetate, Sorbitan Oleate, Mannitol, Sodium Cocoyl Isethionate, Leontopodium Alpinum Meristem Cell Culture, Marrubium Vulgare Extract, Methylpropanediol, Rosa Canina Fruit Extract, Caprylyl Glycol, Cocos Nucifera (Coconut) Oil, Lecithin, Phenylpropanol, Sodium Isethionate.

Frequently Asked Questions

What does ZO Skin Health Clear Renewal do?

ZO Clear Renewal is a corrective retinol treatment designed for oily and blemish-prone skin. It combines 0.3% encapsulated retinol with 1% salicylic acid to help reduce visible blemishes, improve post-acne marks, minimize excess oil, and refine uneven texture.

Is ZO Clear Renewal good for acne-prone skin?

Yes. Clear Renewal is specifically formulated for oily and blemish-prone skin experiencing congestion, excess surface oil, breakouts, and post-blemish discoloration.

Does ZO Clear Renewal help fade post-acne marks?

Clear Renewal is designed to improve the appearance of discoloration left behind after blemishes. Its combination of retinol, salicylic acid, and tone-supporting ingredients helps promote a more even-looking complexion.

What percentage of retinol is in ZO Clear Renewal?

ZO Clear Renewal contains 0.3% retinol delivered through the brand’s proprietary ZO-RDS™ encapsulation system.

Does ZO Clear Renewal contain salicylic acid?

Yes. The formula contains 1% salicylic acid to help exfoliate within pores, remove excess oil, and improve visible congestion.

What is the difference between ZO Clear Renewal and Retinol Skin Brightener 0.3?

Both products contain 0.3% encapsulated retinol and use ZO-RDS™ technology.

Clear Renewal is specifically formulated for oily and blemish-prone skin, targeting visible breakouts, excess oil, congestion, and post-acne marks.

Retinol Skin Brightener 0.3 focuses primarily on uneven pigmentation, dullness, and visible discoloration.

Can ZO Clear Renewal be used every day?

The manufacturer’s recommended regimen begins with one application daily during the first week, followed by twice-daily use thereafter.

Application frequency should be adjusted according to individual skin tolerance.

Can ZO Clear Renewal be used in the morning?

Yes. The manufacturer’s instructions allow morning or evening application.

When used during the day, a broad-spectrum sunscreen rated SPF 30 or higher should be applied as the final skincare step.

Can ZO Clear Renewal be used with benzoyl peroxide?

The manufacturer recommends consulting a physician before combining Clear Renewal with benzoyl peroxide, additional salicylic acid products, topical antibiotics, or oral isotretinoin.

Is ZO Clear Renewal suitable for sensitive skin?

Clear Renewal uses encapsulated retinol technology designed to minimize visible irritation. However, the combination of retinol and salicylic acid may still cause dryness, peeling, or sensitivity.

Individuals with sensitive or compromised skin should seek professional guidance before introducing the treatment.

How long does ZO Clear Renewal take to work?

Visible improvements depend on individual skin condition, treatment consistency, and tolerance. The manufacturer describes improvements in post-blemish marks, excess oil, and skin texture but does not provide a specific clinical results timeline in the supplied information.